Description

Premium Selank 10mg – High-Purity Research Peptide

Product Overview

If you are looking for selank for laboratory research, Cocer Peptides supplies a high-purity, research-grade version of this synthetic heptapeptide. It is a synthetic analogue of the endogenous immunomodulatory peptide tuftsin, with the sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro, as documented in the NIH PubMed database. This compound was developed at the Institute of Molecular Genetics of the Russian Academy of Sciences, with research exploring its potential anxiolytic and nootropic properties.

Researchers investigating this peptide typically require research-grade material with complete analytical documentation. Every batch from Cocer Peptides includes a Certificate of Analysis (COA) showing HPLC purity and mass spectrometry confirmation. Its mechanism is studied through multiple pathways, including modulation of GABAergic neurotransmission, inhibition of enkephalin-degrading enzymes, and regulation of brain-derived neurotrophic factor (BDNF) expression.

Regulatory Notice: This product is supplied strictly for laboratory research use only and is not intended for human or veterinary use. Selank is not approved by the Medicines and Healthcare products Regulatory Agency (MHRA) or the FDA for any indication. Clinical data is primarily drawn from Russian-language studies that have not been replicated in Western populations.

Product Specifications

Mechanism of Action

Enkephalinase Inhibition

Research published in NIH PubMed has demonstrated that selank dose-dependently inhibits enzymatic hydrolysis of plasma enkephalin, with an IC50 of 15 microM. The study found that it was more potent than peptidase inhibitors bacitracin and puromycin in inhibiting enkephalinases. These results suggest that the high efficiency of this peptide in anxiety-related research models may be due to its ability to inhibit enkephalin hydrolysis.

GABAergic Modulation

This compound is studied for its effects on the GABAergic system. Research suggests that it may act as an allosteric modulator of the GABA-A receptor, though direct high-affinity binding has been difficult to demonstrate. Studies have examined its effects on gene expression involved in GABAergic neurotransmission, providing insight into its potential mechanism of action.

BDNF Regulation

Research indexed in NIH PubMed has shown that selank can regulate brain-derived neurotrophic factor (BDNF) content in the hippocampus and prefrontal cortex. In a rat model of ethanol-induced memory impairment, it prevented the formation of memory and attention disturbances, with involvement of the neurotrophin mechanism related to BDNF production.

Research Applications

Anxiety Research Models

The most extensively studied application is in anxiety research. A randomised controlled trial published in NIH PubMed compared monotherapy with phenazepam to complex treatment with this peptide and phenazepam in patients with anxiety disorders. The study found that combined treatment decreased the level of undesirable side-effects of phenazepam, including attention and memory impairment, asthenia, and sedation. However, no Western peer-reviewed RCT for selank in anxiety disorders is registered on ClinicalTrials.gov or indexed in PubMed as of 2026.

Cognitive Function Research

This peptide has been studied for its potential cognitive-enhancing effects. Research in animal models has demonstrated that it produces cognitive-stimulating effects and prevents ethanol-induced memory and attention disturbances. Studies have also examined its effects on learning and memory impaired by damage to the noradrenergic brain system.

Immunomodulatory Research

As a tuftsin analogue, selank shares structural similarities with the endogenous immunomodulatory peptide tuftsin (Thr-Lys-Pro-Arg). Research on tuftsin published in NIH PubMed has demonstrated its role in stimulating phagocytic activity of macrophages and polymorphonuclear cells. This relationship provides a basis for investigating its immunomodulatory properties.

Quality and Purity

Every batch of Cocer Peptides selank undergoes rigorous quality control:

• ≥99% purity verified by HPLC

• Molecular weight confirmed by mass spectrometry

• Batch number matching the vial label

• Certificate of Analysis (COA) available on request

Independent analysis has noted that products labeled as this peptide sold through online vendors without prescription have received no FDA quality oversight and carry risks including incorrect concentration, contamination, and misidentified compound identity. The General Pharmaceutical Council (GPhC) advises consumers to verify supplier credentials when purchasing research compounds online. For those seeking selank for research, batch-level analytical documentation is essential.

Frequently Asked Questions

What is Selank?

Selank is a synthetic heptapeptide analogue of the endogenous immunomodulatory peptide tuftsin, with the sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro. It is studied in laboratory research for potential anxiolytic and nootropic properties.

Is Selank approved for medical use?

No. It is not approved by the MHRA or FDA for any indication. It is approved only in the Russian Federation for generalized anxiety disorder and neurasthenia. Clinical data are drawn from Russian-language studies that have not been replicated in Western populations.

What is the purity of Cocer Peptides Selank?

Our selank is provided at ≥99% purity, verified by HPLC with third-party testing.

How should Selank be stored?

Store lyophilized powder at -20°C for long-term stability. Reconstituted material should be stored at 2–8°C and used promptly following standard laboratory protocols.

Is this product suitable for human use?

No. This product is supplied strictly for research purposes only and is not intended for human or veterinary use. No peptide therapy is FDA-approved for any psychiatric condition as of 2026.

Conclusion

Selank represents a research tool for investigating neuropeptide mechanisms, including enkephalinase inhibition, GABAergic modulation, and BDNF regulation. For scientists seeking this peptide for laboratory applications, Cocer Peptides offers high-purity material with complete analytical documentation and batch-specific COA support. Researchers purchasing selank should ensure the material is used solely for legitimate in-vitro research purposes.

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